Dr. Jeffry N. Bruce
Dr. Bruce is a leading authority on complex tumors of the brain and skull base.  He leads a multidisciplinary effort as Co-Director of the Columbia Neurosurgery Brain Tumor Center and Director of Skull Base Surgery specializing in the surgical treatment of gliomas, meningiomas, pituitary tumors, skull base tumors, craniopharyngiomas and pineal tumors.  His surgical expertise includes extensive experience with minimally invasive techniques and stereotactic surgery as well as surgical alternatives such as radiosurgery.  This broad expertise allows treatment to be tailored and optimized for individual patients according to their needs.

Meagan Smith

Team Support:
Aileen Casanova


Sharon L. Wardlaw, MD
Dr. Wardlaw is Professor of Medicine and the Robert C. and Veronica Atkins Professor of Obesity Research at the College of Physicians & Surgeons and Director of the Neuroendocrine Unit at Columbia University College of Physicians & Surgeons. Dr. Wardlaw has undertaken clinical neuroendocrine research for over 25 years ranging from studies of normal pituitary physiology to the diagnosis and treatment of pituitary diseases, including prolactinomas, acromegaly, Cushing’s disease and lymphocytic hypophysitis. She has published over 100 peer-reviewed articles in the fields of neuroendocrinology and obesity. Ongoing clinical studies develop biomarkers to assess brain melanocortin activity in humans and investigate diagnostic tests for the differential diagnosis of ACTH-dependent Cushing’s syndrome and medical therapies for prolactinomas.  Dr. Wardlaw practices in the Neuroendocrine Unit and specializes in prolactinomas and Cushings disease.

Pamela U. Freda, MD
Dr. Pamela Freda is Associate Professor of Medicine, College of Physicians & Surgeons, Columbia University and Clinical Director of the Neuroendocrine Unit of Columbia University. Dr. Freda graduated from Harvard College and received her MD from Columbia College of Physicians & Surgeons. She completed her Medicine training at The New York Presbyterian Hospital and Fellowship in Endocrinology at Columbia, College of P & S. Dr. Freda is board Certified in Endocrinology, Diabetes & Metabolism. Dr. Freda serves on the Endocrine Society Self-Assessment Committee Member, as a Quality Reviewer of the Pituitary sections of ‘Up to Date Endocrinology’ and served as the Chair of the Endocrine Society Task force for the Clinical Guidelines on Pituitary Incidentalomas . Dr. Freda’s conducts clinical and translational studies in patients with pituitary tumors, in particular acromegaly and nonfunctioning pituitary tumors.  Dr. Freda also studies outcomes of pituitary tumor therapy, including surgery for pituitary tumors. Dr. Freda practices in the Neuroendocrine Unit and her clinical interests are acromegaly and other pituitary tumors.

John C. Ausiello, M.D.
Dr. Ausiello is Assistant Professor of Clinical Medicine at the College of Physicians & Surgeons, Columbia University. He graduated from Harvard College and Harvard Medical School. He completed his internship and residency in Internal Medicine at Massachusetts General Hospital followed by a year as a Research Fellow at College of Physicians & Surgeons, Columbia University. He completed his training in Endocrinology and Metabolic Disorders at College of Physicians & Surgeons, Columbia University. He is board certified in Internal Medicine and Endocrinology, Diabetes & Metabolism. Dr. Ausiello’s research interests include growth hormone deficiency and management of pituitary tumor patients. He currently holds a general endocrine practice within the Endocrine Division at Columbia University Medical Center with a focus on metabolic bone disease, thyroid and neuroendocrine diseases. Dr. Ausiello is a primary attending of the Pituitary Surgery Hospital Team where he cares for patients who have undergone surgery by our Neurosurgeon Dr. Jeffrey Bruce.

Gabrielle Page-Wilson, M.D.
Dr. Gabrielle Page-Wilson is an Assistant Professor of Medicine in the Division of Endocrinology at Columbia University. She graduated from Harvard College with a degree in Psychology, and earned her M.D. from Harvard Medical School. Dr. Page-Wilson completed her internship and residency training in Internal Medicine at Brigham and Women’s Hospital in Boston and her Endocrinology, Diabetes & Metabolism fellowship training at Columbia University Medical Center. She is board certified in Internal Medicine and Endocrinology, Diabetes & Metabolism. Dr. Page-Wilson research interests include novel approaches to the diagnosis and treatment of pituitary tumors with a special focus on Cushing’s disease and prolactinomas. Dr. Page-Wilson attends on the inpatient Endocrinology consult service and in the outpatient General Endocrine clinic at the Columbia University Medical Center. Dr. Page-Wilson is a primary attending on the Pituitary Surgery Hospital Team. Dr. Page-Wilson sees patients in the Neuroendocrine Unit. Her special clinical interests include Cushing’s Syndrome, Hyperprolactinemia, Menopause, and PCOS.


Dr. Steve R. Isaacson
Dr. Isaacson is board certified in both Radiation Oncology and Otolaryngology-Head and Neck Surgery and is recognized for his clinical expertise in all applications of ionizing radiation for the treatment of benign and malignant brain, spine, and skull base tumors. He has a special interest in radiosurgery and has devoted his career to its development. Dr Isaacson has been the Co-Director of the Center for Radiosurgery (Gamma Knife [tm]) at the Columbia University Medical Center campus of the NY Presbyterian Hospital since its inception in 1998.  Since that time, he has treated over 3000 patients.  Dr. Isaacson is also Clinical Professor of Radiation Oncology (Neurological Surgery) at Columbia University. In that position he has served many years as an educator and mentor.


Dr. Alex Khandji